Case Report of International Journal of Case Reports
The emergence of bladder dysfunction secondary to lupus cystitis in a patient with established lupus nephritis: the first case from Pakistan
Naveed Ahmed Mahar1, Syed Arsalan Shehzad Shah2, Hira Maab3, Sara Rasheed Kalwar2, Murli Lal4, Asad Shahzad Hassan4
1Assistant Professor, Department of Urology, Sindh Institute of Urology and Transplantation, Pakistan; 2Resident MS Urology, Department of Urology, Sindh Institute of Urology and Transplantation, Pakistan; 3Department of Internal Medicine, Dow University of Health Sciences, Civil Hospital Karachi, Pakistan; 4Professor, Department of Urology, Sindh Institute of Urology and Transplantation, Pakistan
Lupus cystitis is an uncommon manifestation of systemic lupus erythematosus (SLE). We describe the case of a 23-year-old woman with lupus that complained of abdominal pain, vomiting, and diarrhea for one week. Two years back, she was brought with an affirmative history that satisfied the clinical criteria of SLE which was renal biopsy-proven (class V membranous lupus nephritis). On radiologic workup, she was found to have bilateral hydronephrosis and a thick-walled bladder with diverticula. Immunosuppressive therapy was commenced however augmentation cystoplasty had to be opted for as the symptoms did not subside with medical therapy alone.
Keywords: Lupus cystitis systemic lupus erythematosus lupus nephritis
How to cite this article:
Naveed Ahmed Mahar, Syed Arsalan Shehzad Shah, Hira Maab, Sara Rasheed Kalwar, Murli Lal, Asad Shahzad Hassan. The emergence of bladder dysfunction secondary to lupus cystitis in a patient with established lupus nephritis: the first case from Pakistan. International Journal of Case Reports, 2021; 5:253. DOI: 10.28933/ijcr-2021-11-0505
1. Koh JH, Lee J, Jung SM, Ju JH, Park SH, Kim HY, Kwok SK. Lupus cystitis in Korean patients with systemic lupus erythematosus: risk factors and clinical outcomes. Lupus. 2015 Oct;24:1300-7.
2. Yuan S, Ye Y, Chen D, Qiu Q, Zhan Z, Lian F, Li H, Liang L, Xu H, Yang X. Lupus mesenteric vasculitis: clinical features and associated factors for the recurrence and prognosis of disease. InSeminars in arthritis and rheumatism 2014 Jun 1 [Vol. 43, No. 6, pp. 759-766]. WB Saunders.
3. Tsushima Y, Uozumi Y, Yano S. Reversible thickening of the bowel and urinary bladder wall in systemic lupus erythematosus: a case report. Radiation medicine. 1996 Mar 1;14:95-7.
4. Kinoshita K, Kishimoto K, Shimazu H, Nozaki Y, Sugiyama M, Ikoma S, Funauchi M. Two cases of lupus cystitis with no bladder irritation symptoms. Internal Medicine. 2008;47:1477-9.
5. KOIKE T, TAKABAYASHI K. Lupus cystitis in the Japanese. Internal medicine. 1996;35:87-8.
6. Weisman MH, McDanald EC, Wilson CB. Studies of the pathogenesis of interstitial cystitis, obstructive uropathy, and intestinal malabsorption in a patient with systemic lupus erythematosus. The American journal of medicine. 1981 Apr 1;70:875-81.
7. Nakauchi Y, Suehiro T, Tahara K, Kumon Y, Yasuoka N, Ohashi Y, Kawada M, Hashimoto K. Systemic lupus erythematosus relapse with lupus cystitis. Clinical and experimental rheumatology. 1995 Sep 1;13:645-8.
8. Boye E, Morse M, Huttner I, Erlanger BF, MacKinnon KJ, Klassen J. Immune complex-mediated interstitial cystitis as a major manifestation of systemic lupus erythematosus. Clinical immunology and immunopathology. 1979 May 1;13:67-76.
9. Marques MR, Matos C, Oliveira S. Enteritis and cystitis-a cause of abdominal pain in lupus. Acta reumatologica portuguesa. 2009 Apr 1;34[2A]:241-5.
10. Nishizaki Y, Tamaki H, Yukawa S, Matsui Y, Okada M. Comparison between Japanese and non-Japanese features of lupus cystitis based on case reports including novel therapy and a literature review. Internal Medicine. 2011;50:961-8.
CC BY 4.0
This work and its PDF file(s) are licensed under a Creative Commons Attribution 4.0 International License.