The emergence of bladder dysfunction secondary to lupus cystitis in a patient with established lupus nephritis: the first case from Pakistan


The emergence of bladder dysfunction secondary to lupus cystitis in a patient with established lupus nephritis: the first case from Pakistan


Naveed Ahmed Mahar1, Syed Arsalan Shehzad Shah2, Hira Maab3, Sara Rasheed Kalwar2, Murli Lal4, Asad Shahzad Hassan4

1Assistant Professor, Department of Urology, Sindh Institute of Urology and Transplantation, Pakistan; 2Resident MS Urology, Department of Urology, Sindh Institute of Urology and Transplantation, Pakistan; 3Department of Internal Medicine, Dow University of Health Sciences, Civil Hospital Karachi, Pakistan; 4Professor, Department of Urology, Sindh Institute of Urology and Transplantation, Pakistan


Lupus cystitis is an uncommon manifestation of systemic lupus erythematosus (SLE). We describe the case of a 23-year-old woman with lupus that complained of abdominal pain, vomiting, and diarrhea for one week. Two years back, she was brought with an affirmative history that satisfied the clinical criteria of SLE which was renal biopsy-proven (class V membranous lupus nephritis). On radiologic workup, she was found to have bilateral hydronephrosis and a thick-walled bladder with diverticula. Immunosuppressive therapy was commenced however augmentation cystoplasty had to be opted for as the symptoms did not subside with medical therapy alone.


Keywords: Lupus cystitis systemic lupus erythematosus lupus nephritis

Free Full-text PDF


How to cite this article:

Naveed Ahmed Mahar, Syed Arsalan Shehzad Shah, Hira Maab, Sara Rasheed Kalwar, Murli Lal, Asad Shahzad Hassan. The emergence of bladder dysfunction secondary to lupus cystitis in a patient with established lupus nephritis: the first case from Pakistan. International Journal of Case Reports, 2021; 5:253. DOI: 10.28933/ijcr-2021-11-0505


References:

1. Koh JH, Lee J, Jung SM, Ju JH, Park SH, Kim HY, Kwok SK. Lupus cystitis in Korean patients with systemic lupus erythematosus: risk factors and clinical outcomes. Lupus. 2015 Oct;24[12]:1300-7.
2. Yuan S, Ye Y, Chen D, Qiu Q, Zhan Z, Lian F, Li H, Liang L, Xu H, Yang X. Lupus mesenteric vasculitis: clinical features and associated factors for the recurrence and prognosis of disease. InSeminars in arthritis and rheumatism 2014 Jun 1 [Vol. 43, No. 6, pp. 759-766]. WB Saunders.
3. Tsushima Y, Uozumi Y, Yano S. Reversible thickening of the bowel and urinary bladder wall in systemic lupus erythematosus: a case report. Radiation medicine. 1996 Mar 1;14[2]:95-7.
4. Kinoshita K, Kishimoto K, Shimazu H, Nozaki Y, Sugiyama M, Ikoma S, Funauchi M. Two cases of lupus cystitis with no bladder irritation symptoms. Internal Medicine. 2008;47[16]:1477-9.
5. KOIKE T, TAKABAYASHI K. Lupus cystitis in the Japanese. Internal medicine. 1996;35[2]:87-8.
6. Weisman MH, McDanald EC, Wilson CB. Studies of the pathogenesis of interstitial cystitis, obstructive uropathy, and intestinal malabsorption in a patient with systemic lupus erythematosus. The American journal of medicine. 1981 Apr 1;70[4]:875-81.
7. Nakauchi Y, Suehiro T, Tahara K, Kumon Y, Yasuoka N, Ohashi Y, Kawada M, Hashimoto K. Systemic lupus erythematosus relapse with lupus cystitis. Clinical and experimental rheumatology. 1995 Sep 1;13[5]:645-8.
8. Boye E, Morse M, Huttner I, Erlanger BF, MacKinnon KJ, Klassen J. Immune complex-mediated interstitial cystitis as a major manifestation of systemic lupus erythematosus. Clinical immunology and immunopathology. 1979 May 1;13[1]:67-76.
9. Marques MR, Matos C, Oliveira S. Enteritis and cystitis-a cause of abdominal pain in lupus. Acta reumatologica portuguesa. 2009 Apr 1;34[2A]:241-5.
10. Nishizaki Y, Tamaki H, Yukawa S, Matsui Y, Okada M. Comparison between Japanese and non-Japanese features of lupus cystitis based on case reports including novel therapy and a literature review. Internal Medicine. 2011;50[9]:961-8.


Terms of Use/Privacy Policy/ Disclaimer/ Other Policies:
You agree that by using our site, you have read, understood, and agreed to be bound by all of our terms of use/privacy policy/ disclaimer/ other policies (click here for details). This site cannot and does not contain professional advice. The information on this site is provided for general informational and educational purposes only and is not a substitute for professional advice. Accordingly, before taking any actions based upon such information, we encourage you to consult with the appropriate professionals. We do not provide any kind of professional advice. The use or reliance of any information contained on this site or our mobile application is solely at your own risk. Under no circumstance shall we have any liability to you for any loss or damage of any kind incurred as a result of the use of the site or our mobile application or reliance on any information provided on the site and our mobile application. We may publish articles without peer-review. Published articles of authors are open access. Authors hold the copyright and retain publishing rights without restrictions. Authors are solely responsible for their articles published in our journals. Publication of any information in authors’ articles does not constitute an endorsement by us. We make no representation or warranty of any kind, express or implied, regarding the accuracy, adequacy, validity, reliability, availability or completeness of any information that authors provided. more..


CC BY 4.0
This work and its PDF file(s) are licensed under a Creative Commons Attribution 4.0 International License.