Review Article of International Journal of Bioscience and Medicine
SIGNS OF SUCETTABILITY ASSOCIATED WITH EXTRINSIC FACTORS TO FUNGAL INFECTION BY THE GENUS SPOROTHRIX SPP.
Rubens Barbosa Rezende1 *, Larissa Teodoro2
1Faculdade Santa Rita (FASAR), Conselheiro Lafaiete – MG; 2Instituto de Ciências da Saúde da Universidade Paulista (UNIP), Campinas – SP.
Objective: To evaluate the susceptibility to infection by the genus sporothrix spp.; targeting patients with immunosuppression due to the use of inadequate medication, seropositive patients (carriers of Human Immunodeficiency Syndrome – HIV) and alcoholics dependents.
Method: This is an integrative review of the literature available in the PUBMED database, using the descriptors: “Sporotrichosis”, “Fungi” and “Sporothrix”, duly registered in MeSH, using the boolean operator AND. A total of 128 articles were found and evaluated and, at the end, 15 were selected to compose this review. The inclusion criteria were: full articles, available free of charge, published in English between 2010 and 2020.
Results: Sporotrichosis is clinically characterized in fixed cutaneous, lymphocutaneous, disseminated cutaneous and extracutaneous. Frequently the appearance of disseminated cutaneous sporotrichosis occurs especially in immunosuppressed individuals. The four cases evaluated have as etiological agent in common, the genus Sporothrix spp., distinguishing the species, the contagion, clinical aspects and their susceptibility factors.
Conclusion: However, most cases of sporotrichosis are related to a dysfunction of the immune system. As well, the unusual cases characterize a challenge to reliable diagnosis and can often lead to a wrong pharmacological therapy.
Keywords: Sporotrichosis, Fungi, Sporothrix.
How to cite this article:
Rubens Barbosa Rezende, Larissa Teodoro.SIGNS OF SUCETTABILITY ASSOCIATED WITH EXTRINSIC FACTORS TO FUNGAL INFECTION BY THE GENUS SPOROTHRIX SPP.. International Journal of Bioscience and Medicine, 2021; 4:14. DOI: 10.28933/ijbm-2021-05-1005
1. BARROS, M. B. L.; PAES, R. A.; SCHUBACH, A. O. Sporothrix schenckii and Sporotrichosis. Clinical Microbiology Reviews Oct 2011, 24 (4) 633-654.
2. MORA-MONTES HM. Special Issue “Sporothrix and Sporotrichosis”. J Fungi (Basel). 2018 Oct 12;4(4):116. doi: 10.3390/jof4040116. PMID: 30321990; PMCID: PMC6308924.
3. CHAKRABARTI A, BONIFAZ A, GUTIERREZ-GALHARDO MC, MOCHIZUKI T, LI S. Global epidemiology of sporotrichosis. Med Mycol. 2015 Jan;53(1):3-14. doi: 10.1093/mmy/myu062. Epub 2014 Dec 19. PMID: 25526781.
4. VÁSQUEZ-DEL-MERCADO E, ARENAS R, PADILLA-DESGARENES C. Sporotrichosis. Clin Dermatol. 2012 Jul-Aug;30(4):437-43. doi: 10.1016/j.clindermatol.2011.09.017. PMID: 22682194.
5. RODRIGUES AM, DE HOOG GS, DE CAMARGO ZP. Sporothrix Species Causing Outbreaks in Animals and Humans Driven by Animal–Animal Transmission. PLoS Pathog. 2016. 12 (7): e1005638. https://doi.org/10.1371/journal.ppat.1005638.
6. YAP FB. Disseminated cutaneous sporotrichosis in an immunocompetent individual. Int J Infect Dis. 2011;15(10):e727-e729.
7. GARCÍA CARNERO LC, LOZOYA PÉREZ NE, GONZÁLEZ HERNÁNDEZ SE, MARTÍNEZ ÁLVAREZ JA. Immunity and Treatment of Sporotrichosis. J Fungi (Basel). 2018 Aug 20;4(3):100. doi: 10.3390/jof4030100. PMID: 30127270; PMCID: PMC6162376.
8. GANDHI N, CHANDER R, JAIN A, SANKE S, GARG T. Atypical cutaneous sporotrichosis in an immunocompetent adult: Response to potassium iodide. Indian J Dermatol 2016;61:236.
9. PATEL A., MUDENDA V., LAKHI S., NGALAMIKA O. A 27-Year-Old Severely Immunosuppressed Female with Misleading Clinical Features of Disseminated Cutaneous Sporotrichosis. Case Rep Dermatol Med. 2016;2016:9403690.
10. MOREIRA, J. A. S.; FREITAS, D. F. S.; LAMAS, C. C. “The impact of sporotrichosis in HIV-infected patients: a systematic review,” Infection, vol. 43, no. 3, pp. 267–276, 2015.
11. BARROS NM, PESSOA AS, BROTAS AM. Systemic sporotrichosis in an alcoholic patient. An Bras Dermatol. 2020;95(3):376-378.
12. OROFINO-COSTA, R.; MACEDO, P. M.; RODRIGUES, A. M.; BERNARDESENGEMANN, A. R. Sporotrichosis: an update on epidemiology, etiopathogenesis, laboratory and clinical therapeutics. An Bras Dermatol., 92 (2017), pp. 606-620.
13. PASALA, S.; BARR, T.; MESSAOUDI, I. Impact of Alcohol Abuse on the Adaptive Immune System. Alcohol Res., 37 (2015), pp. 185-197.
14. BENVEGNÚ, A. M.; STRAMARI, J.; DALLAZEM, L. N. D.; CHEMELLO, R. M. L.; BEBER, A. A. C. Disseminated cutaneous sporotrichosis in patient with alcoholism. Rev. Soc. Bras. Med. Trop. 2017, 50 (6), 871-873.
15. QUEIROZ-TELLES, F., BUCCHERI, R., & BENARD, G. Sporotrichosis In Immunocompromised Hosts. Journal of Fungi, 2019, 5(1), 8.
CC BY 4.0
This work and its PDF file(s) are licensed under a Creative Commons Attribution 4.0 International License.