Ana Luiza Batista de Lima1, Carina Scanoni Maia2, Luciana Maria Silva de Seixas Maia3, Danielli Matias de Macêdo Dantas4, José de Castro Neto Júnior5,Juliana Pinto de Medeiros*6

1,2,3,6Universidade Federal de Pernambuco, Departamento de Histologia e Embriologia. 4Unidade Acadêmica de Serra Talhada da UFRPE, 5Universidade Federal do Rio Grande do Norte.

International Journal of Bioscience and Medicine

Objective: To evaluate the therapeutic effect of cyanobacteria Arthrospira sp. in the evolution of periodontal disease.

Methods: Eight rats, aged 90 days weighing 280 ± 300g, were used from the Animal Experimentation Center Animal Hospital of the Department of Pharmaceutical Sciences of the Federal University of Pernambuco. After an adaptation period of 10 days, the animals were randomly divided into three groups, namely: Group I – Control Rats, without administration of cyanobacteria; Group II – Rats with periodontal disease without administration of cyanobacteria; Group III – Rats with periodontal disease with cyanobacteria administration. All animals were induced to periodontitis, which was made by ligature with cotton thread, and this wire was placed around the gingival sulcus of the left upper first molar, with this application there was accumulation of residues, causing the formation of dental biofilm.

Results: After the morphological analysis of the experimental groups, we observed that there was a significant effect among the studied groups, where the periodontal ligament was preserved (treated group) or showed absence of tissue integrity (untreated group).

Conclusion: The administration of Arthrospira sp. in rats with periodontal disease, suggests to be an important ally in the fight against the progression of periodontitis, thus acting in the control of this disease.

Keywords:periodontal disease, rats, spirulina, functional supplement.

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How to cite this article:
Ana Luiza Batista de Lima, Carina Scanoni Maia, Luciana Maria Silva de Seixas Maia, Danielli Matias de Macêdo Dantas, José de Castro Neto Júnior,Juliana Pinto de Medeiros. EVALUATION OF PERIODONTAL DISEASE IN RATS SUBMITTED TO THE ADMINISTRATION OF CYTHOCBACTERIA ARTHROSPIRA SP. (“SPIRULINA SP.”) AS A FUNCTIONAL SUPPLEMENT. International Journal of Bioscience and Medicine, 2020; 4:11. DOI: 10.28933/ijbm-2020-03-1505


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