Recent Articles

  • Inflammatory Processes, Viral Infections and Dental Practice during Covid-19

    The mouth is a natural reservoir of several microorganisms resulting from various ecological determinants, being conducive to contagion, as it is an open system for contamination, to which the oral health team is exposed. This microbiota, in general, is in harmony with the host and is quite relevant, as it contributes to the development of the mucous immune system. However, local and/or systemic changes can result in imbalance and clinical manifestation of diseases in the mouth, as reported in this chapter, about coronavirus, hepatitis, herpes, varicella-zoster, infectious mononucleosis, cytomegalovirus, ebola, and human immunodeficiency virus (HIV). Oral hygiene is essential to maintain harmony between normal oral microbiota and external contamination, and, as is known, the mouth is part of the digestive and respiratory system and, in this moment of the lethal and quite contagious SARS-VOC 2 pandemic, the dental practice needs to reinforce biosafety care and reduce the vulnerability of staff and patients, in order to favor the good practices of home dental care, outpatient and/or hospital assistance.

  • Neuroinflammation

    Inflammation is a complex process, mediated by cellular and molecular mechanisms caused by a response to a tissue damage from an aggressive agent, whether if biological, chemical or physical origin. This process occurs, ultimately, with the purpose of promoting defense, repair and tissue regeneration. The inflammatory process leads to changes in blood vessels that have their diameter and flow altered, with the objective of leading to increased vascular permeability and consequent leakage of fluids and cells into the extracellular space of the affected tissue. This sequence of events generates the cardinal signs of inflammation, which are: pain, heat, redness, edema, with loss or alteration of function. The process occurs through mechanisms induced by cytokines and that despite having local manifestation, it can lead to systemic responses involving the whole organism with fever, chills, tremors, tachycardia, leukocytosis, sweating, diuresis and blood dyscrasias. In the cascade of events related to inflammation, there is initially a local stimulus that promotes morphological and functional changes in the attacked tissue that trigger the release of signaling molecules, the defensins that have a chemotactic effect on monocytes, neutrophils and lymphocytes, and pro-inflammatory mediators. that are directly involved in the next inflammatory phases. There is, then, the recognition of aggression and the aggressor agent by the receptors of cells of the immune system and release of inflammatory mediators, of the cyclooxygenase pathway that will release prostaglandin, prostacyclins and thromboxanes and by the lipooxygenase pathway that will produce leukotrienes (Figure 1). Then, there is a modification of the local microcirculation promoting vasodilation, initially arteriolar and subsequently of the venules by the action of histamine release by mast cells, and associated with an increase in local blood flow, generate the cardinal flushing and heat signals.

  • Monitoring Parasitic Contamination of the Beaches Sand and Public Squares of Northeast Brazil: a Comparative Approach

    This work aims to evaluate the parasite presence in the sand of two squares and beaches/parks in the metropolitan region of Recife-PE and João Pessoa-PB, to compare the frequencies of the main parasitological species in these locations. The samples were collected in 2014 from three different depths of the soil (surface, 10 cm, and 20 cm), obtaining 96 samples from the metropolitan regions of Recife-PE and 48 samples from João Pessoa-PB. In Recife were detected a high number of positive samples from beaches (70.8%) and squares (25.7%) compared to João Pessoa, which reached 45.8% and 25%, respectively. Twelve parasite species were identified, distributed predominantly in the samples collected in 10 and 20 cm. In Pernambuco, the species Giardia lamblia, Cryptosporidium spp., and Endolimax nana were the most recurrent on the beaches, while Toxocara sp. and Iodamoeba butschilii were more frequent in the parks. In the Paraíba were identified only Cryptosporidium spp. and Entamoeba histolytica/E. dispar on the beaches. While Ancylostoma sp., Cryptosporidium spp, and Entamoeba histolytica/E. dispar were the most recurrent in the Paraíba squares. This study highlights the contamination of parasites in public environments (squares/beaches) to alert the need for actions aimed at combating parasites in these places.

  • Recognizing Traditional Chinese Medicine Customs during the COVID-19 Pandemic: A Case Report

    Traditional Chinese Medicine (TCM) is based on the belief of vital energy (qi) within the body and attributes disease with imbalance in energies (yin and yang). The COVID-19 pandemic has necessitated unique physical barriers, including increased physical distancing, use of personal protective equipment (PPE), and telehealth services, which complicate existing efforts to understand alternative health practices. This case report highlights the importance of cultural competency training for healthcare providers, as evident in improved patient care when recognizing and acknowledging TCM customs in association with the COVID-19 pandemic.

  • Effect of RevX solution adjunct to standard therapy in a patient with metastatic lung adenocarcinoma: A case report

    RevX solution is a liquid fermented grain extract obtained through a unique extraction technology, and its ingredients contain phytosterols, sulfonamides, organic acids, and anti-inflammatory substances. The adjunct treatment of RevX for lung adenocarcinoma has not yet been surveyed in vitro or in vivo experiments. A 71-year-old woman was diagnosed with lung adenocarcinoma. She underwent the targeted therapy and continually took the RevX solution (3 to 5 ml per day). Sixteen months after diagnosis and targeted therapy, multiple lung metastases appeared. After the second-line targeted therapy and wedge resection for 16 months, the patient was still alive. The distinct improvement of hypodynamia and fewer complication was found during targeted therapy treatment complemented with the RevX solution for longer than 4 years. Thus, the RevX solution might potentially be an adjuvant therapy for patients with metastatic lung adenocarcinoma.

  • Integrative and Complementary Practices: the Therapeutic Benefits of Aromatherapy and Chromotherapy

    Objective: To understand the availability and use of integrative and complementary practices by the SUS; as well as to evaluate two of the various therapy options, chromotherapy and aromatherapy, in relation to their effectiveness and benefits for patients. Method: This is an integrative review of the literature available in the PUBMED and SciELO database, using the descriptors: “Aromatherapy”, “Chromotherapy” and “Alternative Therapy”, duly registered in MeSH/DeCS, using the boolean operator AND. Twenty-nine articles were found, 25 evaluated and, at the end, 11 selected to compose this review. The inclusion criteria were: complete articles, available free of charge, published in English, from 2012 to 2020. Results: The inclusion of integrative and complementary practices (ICPs) in the Sistema Único de Saúde (SUS) was through the Política Nacional de Práticas Integrativas e Complementares (PNPIC), supported through the Portaria GM/ MS no 971, on May 3, 2006. Brazil is the country characterized as a world reference in the field of ICPs in basic attention. Conclusion: However, several cases of use of chromotherapy and aromatherapy as alternative therapies to promote patient’s health, relieve pain and, among other unique symptoms in each case, were evaluated, and the therapies used proved their efficacy and safety for patients, as well as improved the quality of life of these people.


    Objectives: To review in the literature the perception of ICU health professionals, as members of an interdisciplinary team. Methods: This is an integrative literature review, carried out between July and August 2020. The data collection took place between the years 2012 to 2020, in the electronic databases PubMed (National Library of Medicine and National Institute of Health – USA) and Scielo (Scientific Electronic Library Online), through the DeCS (health descriptors) “patient care team”, “intensive care units” and “health”, in English and Portuguese. Results: After applying the eligibility criteria for this review, 7 articles were selected, read in full. The results showed the existence of division and fragmentation of work; lack of communication between team members and users; hierarchy of power and ethical conflict within the multiprofessional team; and inadequate working conditions. Conclusion: This research made it possible to recognize the weaknesses experienced by the multiprofessional ICU team and to understand the main factors that hinder the team’s work.

  • Occurrence of Anemophilous Fungi in the Special Collection of the Agricultural Sciences Center Library of the Federal University of Paraíba

    Objectives: The work objective was to verify the occurrence of anemophilous fungi present in the air and on the surface of books in the special and rare collection of the CCA/UFPB Library. To the isolation of anemophilous fungi present in the air, there used a direct exposure method, in which plates were exposed for 20 min. Methods: To the isolation of anemophilous fungi present in the air, there used a direct exposure method, in which plates were exposed for 20 min. The fungi collection from the surfaces of the books, it was performed through rubbing sterile swabs along the entire length of the cover and placed in a test tube with a saline solution. Then, it sowed the samples in Petri dishes containing culture medium. The plates with samples of fungi from the air and the surface of the books, it was incubated in an oven at 28 ºC. After the growth of the colonies, the identification was based on macro and micromorphological analyzes. Results: There obtained a total of 688 isolates of anemophilous fungi belonging to 14 taxa. Most belong to the group of asexual fungi. The most frequent taxa were Penicillium (61.5%), sterile mycelia (23.5%), and Cladosporium (7.6%). Conclusion: The Library presented an important presence of several fungal genera in its spaces, favoring the biodeterioration of historical documents, besides being able to compromise the health of employees and visitors.


    Introduction: Osteoarthritis (OA) is the most common rheumatologic disease in the world and the elderly are the most affected, although there is no defined age for its onset. Obesity is a risk factor, with healthy eating habits and physical exercise practices being recommended for treatment and prevention. The pharmacological treatment for OA is oral chondroprotective agents and viscosupplements, although anti-inflammatory drugs are widely prescribed, they do not cause clinical improvement, they only treat the symptoms of the disease. Objective: This study gathered articles from clinical trials in Brazil with the purpose of investigating whether the pharmacological treatments used are effective. Methods: The electronic platforms used for data collection were: Scielo, CAPES Journal Portal and Google Academic. Articles published in the last six years with clinical trials in Brazil were considered. Articles involving surgeries, those that used physiotherapy as an adjunct therapy and those that used animal or non-human research in their research were excluded. The search was through the descriptors: hyaluronic acid, glucosamine and chondroitin. Results: The search resulted in six articles, in which three were used chondroprotectors and the other three viscosupplements. Chondroprotectors were effective in 66.66% of clinical trials and viscosupplements in 100%. Conclusion: Pharmacological treatments for OA showed high efficacy, however the sample of the present work was small, thus, further studies are needed to confirm the results obtained.

  • Sensory integration therapy (SIT) in the assistance to child population: integrative literature review

    Introduction: Sensory Integration is a neurological process that organizes and integrates sensory information in an appropriate way, causing the body to produce adaptive responses. Ayres created the theory and the Sensory Integration Therapy (SIT) to study this brain function and the learning disorders in children that he faced in his professional practice. Objective: To analyze, through a literature review, the benefits of Sensory Integration Therapy in assisting the development of the Child Population. Methods: Searches were made in the BVS, LILACS and Scielo databases, including articles in Portuguese, English and Spanish and excluding theses, dissertations, monographs and repeated articles. After analyzing the articles, 13 of them were selected to compose the present results. Results: After the Sensory Integration Therapy, children started to have better communication, writing and articulation of words, in addition to better social interaction with their own family and with other children. The use of Therapy was seen in contexts of food selectivity and autism, helping the child to identify and organize the information and stimuli received, also influencing the Daily Living Activities such as eating, dressing and cleaning. Conclusion: Sensory Integration Therapy has been increasingly used and required of occupational therapists, to assist the child population for the benefits generated by this approach such as improvement in ADLs and social participation.