American Journal of Surgical Research and Reviews


Research Article of American Journal of Surgical Research and Reviews Translational Medicine and Autologous Fat Transfer: From bench to bedside. Regenerative and proliferative potential of adipose tissue Andrea Edoardo Bianchi, MD1,2, Antonio Lucchi, MD1, Riccardo Luoni Orsi, DMD1, Luigi Clauser, MD1 1Unit of Maxillo-Facial Surgery, Istituto Stomatologico Italiano, Via Pace, 21, 20122 MILANO, Italy; 2University UniCamillus, Via di Sant’Alessandro, 8, 00131 ROME, Italy Aim: Autologous fat transfer (AFT) for the correction of maxillofacial defects was first reported at the end of the 19th century. AFT was introduced as a way of improving facial esthetics and in the last few years has expanded into applications in craniomaxillofacial reconstructive surgery and regenerative therapy. This protocol is part of translational medicine. The aim of translational medicine, or translational science, is to combine disciplines, resources, expertise, and techniques based on three main pillars: bench, bedside, and community. The primary goals to coalesce assets of various natures to significantly improve the global healthcare system. AFT is thus part of translational medicine in tissue healing, regeneration and augmentation. Methods: Several techniques have been suggested for harvesting and grafting the fat. The Authors follow Coleman’s technique with centrifugation and infiltration using different types and sizes of cannulas. Conclusion: This review provides a fairly comprehensive summary of the many exciting possibilities that exist in the field of facial fat grafting. Five clinical cases are presented and discussed. Translational medicine is the basis of this new reconstructive and regenerative field of science and research. Keywords: Regenerative medicine, translational medicine, lipofilling, fat grafting, adipose-derived-stem-cells, fat graft survival, fat graft processing, maxillofacial surgery, soft tissue reconstruction, stem cells, bench to bedside ...


Case Report of American Journal of Surgical Research and Reviews Single stitch Open interval appendectomy; when and why Dr.jitendra kumar Saroj1, Dr santosh Gautam2 1Assistant professor, Department of general surgery Venkateshwara institute of medical sciences, Gajraula, INDIA; 2Assistant professor, Department of general surgery, Prasad institute of medical sciences,Sarojani Nagar Lucknow, Santosh Gautam Appendicitis is a very common cause of acute abdomen. Most of the patient admit in surgical emergency. Diagnosis usually made clinically, sonography sometimes may be helpful. Regarding management there is still controversy exists. Developed country usually performed laparoscopy appendectomy while in developing country surgical management is still in debate. Different surgeons have different opinion either emergency open or laparoscopy appendectomy or interval appendectomy. Even in open appendectomy there is still debate between classical procedure vs small incision. This study favors single stitch surgery rather than classical and laparoscopy appendectomy. this case study supports even better cosmetic and outcome than laparoscopy appendectomy. Keywords: single stitch, interval appendectomy, classical, laparoscopic ...


Research Article of American Journal of Surgical Research and Reviews Blue Round Small Cell tumor: A Surgical Update of DSRCT with review of literature ‘A Grim Affair’ Dr.UwaisRiazUlHasan3 M.Med, Dr.Khathija Hasan M.Med, Dr.Farooq Ahmed Qureshi MS, Dr. Victor Effiong Obong M.B.B.Ch, MWACS, Dr.Abdul Aziz Al Nami M.B.B.S, Dr.Ali Ibrahim AlShaqaqiq M.B.B.S, Dr.Mohammad AbdulMajeed Alghadeer M.B.B.S Dr. Marwan Ahmad AlRayhan M.B.B.S, Dr. Mohammed Ali AlJummah M.B.B.S, Dr.Baqer Ali Aldheen M.B.B.S, Dr. Ali Hussain AlRufayi MD, Dr.ShehlaRiazUlHasan Phd. Dr. Moath AbdulAziz AlMasoud2 M.D, Dr. Noura Al Dossary1 Department of General Surgery, Al Omran General Hospital, Al Hassa, Kingdom of Saudi Arabia. Hospital Director1,Head of department2, Assoc Consultant General Surgeon3 Desmoplastic small round cell tumor (DSRCT) is a tumor derived from the Greek desmos referring to knot and plasis to formation an uncommon soft tissue malignant tumor, mesenchymal in origin and aggressive with a prelidiction for males and advanced at presentation. It was first described as a distinct clinical entity by Gerald WL and Rosai J (7). There are fewer than 200 reported to date. Depending on the primary site of location the Clinical manifestations vary. As most arise from the abdomen and pelvis they remain asymptomatic till they attain a huge size. Other reported sites are the skull, thorax, and paratesticular region (10,13). We report the case of a 19 yr old male who had non specific abdominal discomfort with asthenia for a period of six months and was referred to us for evaluation of left supraclavicular nodes. The prognosis of Desmoplastic small round cell tumor (DSRCT) is poor with few surviving less than two years. Keywords: Blue round, Desmoplastic small round cell tumor, Radiology, Multimodal therapy ...


Research Article of American Journal of Surgical Research and Reviews Treatment of “En Coupe De Sabre “ Linear Scleroderma. Soft Tissue Augmentation and Regeneration by Autologous Fat Transfer Luigi Clauser,MD1, Antonio Lucchi,MD1, Carolina Sannino,MD1, and Andrea Edoardo Bianchi,MD1, 2 1Unit of Maxillo-Facial Surgery, Istituto Stomatologico Italiano, Via Pace, 21, 20122 Milano, Italy; 2 University UniCamillus ,Via di Sant’Alessandro,8,00131 Roma,Italy Aim: Frontal linear scleroderma, also known as ‘‘en coup de sabre,’’ is a congenital deformity characterized by atrophy and furrowing of the skin of the front parietal area above the level of the eyebrows. In most cases it occurs as a single paramedian line that may be associated with hypoplasia of underlying structures and facial hemiatrophy. In case of a wide lesion many reconstructive strategies have been proposed. The modern approach is aimed at augmentation of the tissue deficiency by using lipostructure and tissue regeneration. Autologous  fat transfer (AFT) seems to be an effective strategy to restore the normal volume and contour of the face while providing a source of adipose-derived stem cells (ADSCs) with a multilineage differentiation potential. Methods: In this report, we present a rare case of linear scleroderma en coupe de sabre which was successfully managed with three stages of  autologous fat grafting. Conclusion: The proposed uses for ADSCs in tissue repair and regeneration are quite impressive. Recent works on ADSCs would suggest that adult cells may prove to be an equally powerful regenerative tool in treating congenital and acquired maxillofacial disorders. More importantly, physicians, researchers and international associations need to cooperate in informing clinicians about what practices are based on evidence  and to encourage support of additional research. There is increasing interest in a possible therapeutic effect of ADSCs from processed lipoaspirate for a wide spectrum of clinical applications in the facial and craniofacial area. AFT can ...

Manuscript Title: The title should be a brief phrase.

Author Information: List full names and affiliation of all authors, including Emails and phone numbers of corresponding author.

Abstract: The abstract should be less than 500 words. Following abstract, a list of keywords and abbreviations should be added. The keywords should be no more than 10. Abbreviation are only used for non standard and long terms.

Introduction: The introduction should included a clear statement of current problems.

Materials and Methods: This section should be clearly described.

Results and discussion: Authors may put results and discussion into a single section or show them separately.

Acknowledgement: This section includes a brief acknowledgment of people, grant details, funds

References: References should be listed in a numbered citation order at the end of the manuscript. DOIs and links to referenced articles should be added if available. Abstracts and talks for conferences or papers not yet accepted should not be cited. Examples Published Papers: 

1. Hongmei YANG. A study on the Management Mode of Modern Vocational Education in China. Global journal of Economics and Business Administration, 2018, 3: 10.DOI: 10.28933/gjeba-2018-07-2301 

Tables and figures: Tables should be used at a minimum with a short descriptive title. The preferred file formats for Figures/Graphics are GIF, TIFF, JPEG or PowerPoint.

Publication fees: We do not charge any submission charges, but authors are required to pay publication fees after their manuscripts are accepted for publication. For authors who receive our invitations, please send us the invitation code to receive the special discount.

Proofreading and Publication: A proof will be sent to the corresponding author before publication. Authors should carefully read the proof to avoid any errors and return the proof to the editorial office. Editorial office will publish the article shortly.

Withdrawal Policy: When you want to withdraw an article, please contact us. We will withdraw/retract it from our system after reviewing your request.

Terms of Use/Privacy Policy/Disclaimer/Other Policies: you agree that by using or receiving our services, you have read, understood, and agreed to be bound by all of our terms of use/privacy policy/ disclaimer/ other policies.

About the journal
The journal is hosted by eSciPub LLC. Our aim is to provide a platform that encourages publication of the most recent research and reviews for authors from all countries.

About the publisher
eSciPub LLC is a publisher to support Open Access initiative located in Houston, Texas, USA. It is a member of the largest community of professional publishers in the United States: the Independent Book Publishers Association. It hosts more than 100 Open Access journals in Medicine, Business & Economics, Agriculture, Biological Sciences, Chemistry, Education, Physical Sciences, Sociology, and Engineering and Technology.

Rapid Response Team
Please feel free to contact our rapid response team if you have any questions. Our customer representative will answer your questions shortly.

American Journal of Surgical Research and Reviews