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Laparoscopic approach for pancreato-splenic abscess from disseminated melioidosis: Surgical outcome and review of literature

Case Report of International Journal of Case Reports Laparoscopic approach for pancreato-splenic abscess from disseminated melioidosis: Surgical outcome and review of literature Hiang Jin Tan, Adrian Kah Heng Chiow, Nita Thiruchelvam, Siong San Tan, Lip Seng Lee Hepatopancreatobiliary Unit, Department of Surgery, Changi General Hospital, Singapore 529889. Melioidosis is a severe systemic infection caused by Burkholderia pseudomallei. It commonly affects the lungs, liver and kidneys. Pancreatic and splenic abscess from melioidosis is rare, with few reports in the literature. We present a series of 4 patients with disseminated melioidosis of pancreas and spleen who required surgical intervention. A MEDLINE database review was conducted. Relevant publications were evaluated and demographic data, clinical, radiological findings as well as management options were collected. We found 10 case reports describing this clinical condition. In our series, median age was 57. Median operative time 260 minutes. All four patients failed trial of antibiotic therapy and required surgery. Three underwent distal pancreatosplenectomy and one underwent splenectomy alone. Laparoscopic distal pancreatosplenectomy was successful in two patients. Median length of stay 11.5 days. No post-operative complications and mortality reported. Surgery is indicated in failed medical therapy and laparoscopic approach is safe and feasible. Keywords: laparoscopic surgery, melioidosis, spleen, pancreas ...

Aromatherapy: Prophylactic and Therapeutic Approach to Diseases of the Respiratory System

Review Article of International Journal of Bioscience and Medicine Aromatherapy: Prophylactic and Therapeutic Approach to Diseases of the Respiratory System Alan Lucena de Vasconcelos1, De Vasconcelos, A.L1; Alex Lucena de Vasconcelos2 MSc. Pharmacist of the Clinical Research Group at Instituto de Ensino e Pesquisa Alberto Ferreira da Costa. ZIP Code: 52.010-075 - Recife, PE - Brazil1. PhD Pharmacist Professor of the Pharmacy Department at the Pernambuco Health College - FPS2 Infectious diseases are a significant public health challenge due to the increasing recognition of new infectious agents and the resurgence of infections until recently controlled. These infectious illnesses constitute many hospital admissions, mainly respiratory focus, which requires high-cost therapy. One of the strategies to prevent injuries leading to hospitalization is reducing the body’s inflammatory response. Thus, aromatherapy seems to be a useful adjuvant therapeutic tool due to the essential oils’ synergistic action with proven anti-inflammatory and antimicrobial properties. Hence, this study proposes an integrated review of the literature on aromatherapy as a tool to be used in prophylaxis and therapy in respiratory system disorders. After passing the criteria of exclusion and content analysis, a set of 124 articles narrowed to 44 articles that support the anti-inflammatory properties of the sesquiterpenes, such as the farnesol. This substance treats the respiratory system and is present in Cymbopogon nardus, Cymbopogon flexuosus, and Rosa damascena. Caryophyllene and its derivatives are present in Syzygium aromaticum, Rosmarinus officinalis, and Cannabis sativa. Besides, α-bisabolol and chamazulene present in Matricaria recutita and Achillea millefolium. Other oils have antibiotic properties that act against gram-positive and gram-negative bacterias according to their constitution’s complexity and interaction with these microorganisms. In this context, some species such as Cinnamomum zeylanicum, Citrus hystrix, Cymbopogon Citratus, Eucalyptus globulus, Eucalyptus odorata, Juniperus communis, Lavandula angustifólia, Lavandula intermedia, Melaleuca leucadendra, Mentha piperita, Pinus sylvestris, Syzygium aromaticum, and ...

Isolated metastasis of hepatocellular carcinoma in the right atrium: a case observed in a university hospital in West Africa (Bouake, Ivory Coast)

Case Report of Open Journal of Gastroenterology and Hepatology Isolated metastasis of hepatocellular carcinoma in the right atrium: a case observed in a university hospital in West Africa (Bouake, Ivory Coast) Jean Baptiste Okon, Mamadou Diakité, Aké Akoun Fabrice, Koffi Kouadio Olivier Claver, Kone Amadou. University hospital center of Bouake, Ivory Coast. University Alassane Ouattara, Medecine department Intracardiac metastases from hepatocellular carcinoma (HCC) are rare and have a poor prognosis. We report an observation in a West African university hospital in a 39-year-old black patient admitted with upper gastrointestinal bleeding. Clinical examination noted signs of cirrhosis, namely hepatocellular failure, portal hypertension, melena and signs of right heart failure against a background of deterioration in general condition (WHO-3). The CT scan showed a focal hepatic lesion with arterial enhancement and portal lavage compatible with HCC and a right intracardiac mass taking contrast. Doppler echocardiography confirmed the presence of a large heterogeneous mass occupying almost the entire right atrium. Palliative and symptomatic treatment was instituted in the patient improving his clinical condition. His death occurred two months after his release. The intracardiac localization of HCC, although rare, is not exceptional and of appalling prognosis. It should be sought in the assessment of the extension of HCC, especially in the presence of signs of cardiac involvement. Keywords: Intracardiac metastasis, Right atrium, Hepatocellular carcinoma, west Africa ...

Astaxanthin: The possible effects of this carotenoid on disease, inflammation and aging control. A meta-analysis

Review Article of International Journal of Food and Nutrition Research Astaxanthin: The possible effects of this carotenoid on disease, inflammation and aging control. A meta-analysis Ferro M.*, Graubard A. and Beauchesne T. FG Scientifica and Science Department at Nutrition Formulators Inc., Miramar, Fl, 10407 N Commerce, Parkway, Miramar, Fl 33025 Miramar, Fl, USA Astaxanthin (ATX), a red pigment that belongs to the xanthophyll subclass of carotenoids, has a strong antioxidant ability and can eliminate singlet oxygen (O2-) as well as hydrogen peroxide (H2O2) and lipid peroxidation. ATX can also prevent mitochondrial dysfunction by permeating and co-localizing within the mitochondria and inhibit the release of cytochrome c resulting from mitochondrial permeabilization and, thus, prevent mitochondrial-mediated apoptotic cell death. Due to its antioxidant capacity and modulating properties of cell signaling, ATX exhibits a variety of beneficial biological activities among them protection against UV damage, anti-inflammatory and immunomodulatory activity, metabolic syndrome (MS) relief, cardioprotective effects, antidiabetic activity, prevention of neuronal damage, anti-aging and anticancer activity. The aim of the present study was to evaluate what has been published about ATX in PubMed/Medline between 2020-2021. The results were distributed in four Tables as follows: Table 1-Publication types; Table 2- Proposal for evaluating the article in vivo; Table 3- Cells markers used in clinical studies in vivo; Table 4- Astaxanthin in human clinical trial. We could observe that the interest of the scientific community has been growing in relation to the benefits of ATX. The results presented in the articles evaluated in this meta-analysis showed us that AXT is already a reality as an option in treatments for various diseases, including glaucoma, heart and vascular injury, type 2 diabetes and fatty liver. We conclude that ATX may not only be a promising nutraceutical as an ally to alternative treatments of the pathologies mentioned above, but ...

Microbiological Analysis and pH Determination of Drinking Water Samples from Public Schools

Research Article of International Research Journal of Public Health Microbiological Analysis and pH Determination of Drinking Water Samples from Public Schools in the Municipality of Recife/PE Rosana Maria da Conceição Silva1, Cléber José da Silva1, Bruno Joaquim de Santana2, Fabrícia Karla da Silva3 Federal University of Pernambuco1, Estacio of Recife University2, Maurício de Nassau University3 Water is considered a finite natural resource and one of the essential elements of life. It is used in various work activities such as agriculture, industry, livestock, public supply, energy generation, among others [15]. According to SPERLING (2006) [38], only 2.493% of the water on the planet is suitable for the consumption of humans and animals and 0.0007% of the water accessible for consumption is present in the atmosphere, rivers and lakes. It is estimated that more than one billion people worldwide do not have access to treated water, as its supply is not made on an equal basis due to population growth, economic activities and uneven distribution contrasted with different populations. between rural and urban areas [3, 21,33,]. Problems related to water shortages in the metropolitan regions of Brazilian states are increasingly present in everyday life, and can be attributed to factors involving administrative processes, such as the high cost of drinking water treatment, pollution of water tables, increased demand for water. consumption and climatic factors. In this sense, the use of water for poor quality consumption is an alternative for regions experiencing shortages and has a direct impact on the health of individuals, especially workers and students, as about 80% of the infectious and parasitic diseases that affect developing countries are due to poor quality water, directly impacting the individual's health [10,17,18,28,36,37]. The water potability standards in Brazil are described in Ordinance GM / MS No. 2,914, of December 12, 2011, which portrays ...

Inflammatory Processes, Viral Infections and Dental Practice during Covid-19

Review Article of International Journal of Dental Research and Reviews Inflammatory Processes, Viral Infections and Dental Practice during Covid-19 Aurora Karla de Lacerda Vidal¹, Mônica Moreira Dias da Cruz2, Angélica Lopes Frade¹, Anna Danielly Almeida do Nascimento¹, Beatriz Santos Borges¹, Cristianne de Barros Santos¹, Fernanda Teles Pereira¹, Laís Azevedo Lins de Holanda¹ 1Institute of Biological Sciences, Oncology Center - Oswaldo Cruz University Hospital of the University of Pernambuco (ICB / CEON - HUOC / UPE); 2Pediatric Oncohematology Center - Oswaldo Cruz University Hospital of the University of Pernambuco (CEONPE - HUOC / UPE) The mouth is a natural reservoir of several microorganisms resulting from various ecological determinants, being conducive to contagion, as it is an open system for contamination, to which the oral health team is exposed. This microbiota, in general, is in harmony with the host and is quite relevant, as it contributes to the development of the mucous immune system. However, local and/or systemic changes can result in imbalance and clinical manifestation of diseases in the mouth, as reported in this chapter, about coronavirus, hepatitis, herpes, varicella-zoster, infectious mononucleosis, cytomegalovirus, ebola, and human immunodeficiency virus (HIV). Oral hygiene is essential to maintain harmony between normal oral microbiota and external contamination, and, as is known, the mouth is part of the digestive and respiratory system and, in this moment of the lethal and quite contagious SARS-VOC 2 pandemic, the dental practice needs to reinforce biosafety care and reduce the vulnerability of staff and patients, in order to favor the good practices of home dental care, outpatient and/or hospital assistance. Keywords: Inflammatory Processes; Viral Infections; Dental Practice; Covid-19 ...